Manuel Lozano started his acting career like many other child actors, making some commercials. When he was nine years old, he was chosen to work with Fernando Fernán Gómez in the Spanish critically acclaimed Butterfly. His performance in this movie won a Goya Award, and a nomination for Young Artist Award. He also starred in another critically acclaimed movie, Eres mi héroe, which won at the Ft. Lauderdale Film Festival. With a Spanish mother and Italian father, Manuel Lozano has dual nationality and lives in Galicia, Spain.